Pharmacokinetics and bioavailability of doxycycline in ostriches (Struthio camelus) at two different dose rates
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Pharmacokinetics and bioavailability of doxycycline in ostriches (Struthio camelus) at two different dose rates
A bioavailability and pharmacokinetics study of doxycycline was carried out on 30 healthy ostriches after a single intravenous (IV), intramuscular (IM) and oral dose of 15 mg/kg body weight. The plasma doxycycline concentration was determined by HPLC/UV at 0 (pretreatment), 0.08, 0.25, 0.5 1, 2, 4, 6, 8, 12, 24 and 48 h after administration. The plasma concentration-time curves were examined us...
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ژورنال
عنوان ژورنال: Journal of Veterinary Science
سال: 2006
ISSN: 1229-845X
DOI: 10.4142/jvs.2006.7.4.327